The Humsafar Trust (HST) Research has played an important role in informing, designing and guiding interventions pertaining to the HIV related risk behaviors of men having sex with men (MSM). Research studies as an integral part of an intervention were in-built into the programs of the HST.

In the field of Social Development, HST has carved its’ niche by extensively studying and linking the clinical data to behavioral data to inform more about the progression of the HIV/AIDS epidemic among MSM. Mental health issues of MSM are extremely important but rarely addressed.

In 2006, the organization initiated a research study on mental health of MSM. Strategic alliance with the Sion Hospital and Medical College has just not resulted into exemplary public-NGO partnership, but it has also facilitated analysis and usage of epidemiological and clinical data for the benefit of larger spectrum of MSM.

HST is the first community based organization that set up its own Institutional Review Board in 2006 with National Institute of Health (NIH) with Federal Wide Assurance (FWA) certification in place.